From 2006-2009, a total of six issues were produced with the original cast who were all in medical school at the time. Prior to the popularity of social media, it had always been the intention to make Medthics more of an open dialogue. At the time, Blogger was the appropriate forum.

Our first attempt at promoting Medthics publically was in 2007, where a panel discussion was held at the University of Western Ontario medical school and can still be found on YouTube.

In 2009, the original cast disbanded for residency. The hectic life of a resident made progression of Medthics limited. Despite this, Medthics #7 was produced for The Canadian Library of Family Medicine. In 2012, Medthics made a larger public display at the Comics and Medicine 3rd International Conference in Toronto

Later that year, Medthics had a venture into academia in the December 2012 edition of the Journal of Medical Humanities.

In August 2013, Medthics #7 was the featured Story of the Month with the Canadian Stories in Family Medicine.

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